Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine

Urgent action is needed to fight the ongoing COVID-19 pandemic by reducing the number of infected people along with the infection contagiousness and severity. Chlorpromazine (CPZ), the prototype of typical antipsychotics from the phenothiazine group, is known to inhibit clathrin-mediated endocytosis...

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Detalles Bibliográficos
Autor principal: Plaze, Marion
Formato: Published Article
Publicado: 2020-05-06
Materias:
Acceso en línea:https://www.biorxiv.org/content/10.1101/2020.05.05.079608v1
https://hdl.handle.net/20.500.12663/1476