Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020
Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with...
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2020-04-03
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| Acceso en línea: | https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000508 https://hdl.handle.net/20.500.12663/2277 |
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Tostmann, Alma et al. 2020-09-29T00:40:43Z 2020-09-29T00:40:43Z 2020-04-03 https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000508 https://hdl.handle.net/20.500.12663/2277 Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies. English COVID-19 Coronavirus Infections Coronavirus Betacoronavirus SARS-CoV-2 Delivery of Health Care Netherlands Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 Eurosurveillance Others Infection prevention and control, including health care workers protection Published Article Protect Health Care Workers / Proteger la Salud de los Trabajadores |
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Organización Panamericana de la Salud |
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Organización Panamericana de la Salud |
| title |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 |
| spellingShingle |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 Tostmann, Alma et al. COVID-19 Coronavirus Infections Coronavirus Betacoronavirus SARS-CoV-2 Delivery of Health Care Netherlands |
| title_short |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 |
| title_full |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 |
| title_fullStr |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 |
| title_full_unstemmed |
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020 |
| title_sort |
strong associations and moderate predictive value of early symptoms for sars-cov-2 test positivity among healthcare workers, the netherlands, march 2020 |
| author |
Tostmann, Alma et al. |
| author_facet |
Tostmann, Alma et al. |
| topic |
COVID-19 Coronavirus Infections Coronavirus Betacoronavirus SARS-CoV-2 Delivery of Health Care Netherlands |
| topic_facet |
COVID-19 Coronavirus Infections Coronavirus Betacoronavirus SARS-CoV-2 Delivery of Health Care Netherlands |
| publishDate |
2020-04-03 |
| format |
Published Article |
| description |
Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.
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| url |
https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000508 https://hdl.handle.net/20.500.12663/2277 |
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AT tostmannalmaetal strongassociationsandmoderatepredictivevalueofearlysymptomsforsarscov2testpositivityamonghealthcareworkersthenetherlandsmarch2020 |
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